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MassTag Polymerase-Chain-Reaction Detection of Respiratory Pathogens, Including a New Rhinovirus Genotype, That Caused Influenza-Like Illness in New York State during 2004–2005

Identifieur interne : 004062 ( Main/Exploration ); précédent : 004061; suivant : 004063

MassTag Polymerase-Chain-Reaction Detection of Respiratory Pathogens, Including a New Rhinovirus Genotype, That Caused Influenza-Like Illness in New York State during 2004–2005

Auteurs : Daryl Lamson ; Neil Renwick ; Vishal Kapoor ; Zhiqiang Liu ; Gustavo Palacios ; Jingyue Ju ; Amy Dean ; Kirsten St. George ; Thomas Briese ; W. Ian Lipkin [États-Unis]

Source :

RBID : ISTEX:D8B17DFBD8924ED07B8E6C1F3E0F0964C6D88BE0

Abstract

In New York State during winter 2004, there was a high incidence of influenza-like illness that tested negative both for influenza virus, by molecular methods, and for other respiratory viruses, by virus culture. Concern that a novel pathogen might be implicated led us to implement a new multiplex diagnostic tool. MassTag polymerase chain reaction resolved 26 of 79 previously negative samples, revealing the presence of rhinoviruses in a large proportion of samples, half of which belonged to a previously uncharacterized genetic clade. In some instances, knowledge of the detected viral and/or bacterial (co)infection could have altered clinical management

Url:
DOI: 10.1086/508551


Affiliations:


Links toward previous steps (curation, corpus...)


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