MassTag Polymerase-Chain-Reaction Detection of Respiratory Pathogens, Including a New Rhinovirus Genotype, That Caused Influenza-Like Illness in New York State during 2004–2005
Identifieur interne : 004062 ( Main/Exploration ); précédent : 004061; suivant : 004063MassTag Polymerase-Chain-Reaction Detection of Respiratory Pathogens, Including a New Rhinovirus Genotype, That Caused Influenza-Like Illness in New York State during 2004–2005
Auteurs : Daryl Lamson ; Neil Renwick ; Vishal Kapoor ; Zhiqiang Liu ; Gustavo Palacios ; Jingyue Ju ; Amy Dean ; Kirsten St. George ; Thomas Briese ; W. Ian Lipkin [États-Unis]Source :
- The Journal of Infectious Diseases [ 0022-1899 ] ; 2006.
Abstract
In New York State during winter 2004, there was a high incidence of influenza-like illness that tested negative both for influenza virus, by molecular methods, and for other respiratory viruses, by virus culture. Concern that a novel pathogen might be implicated led us to implement a new multiplex diagnostic tool. MassTag polymerase chain reaction resolved 26 of 79 previously negative samples, revealing the presence of rhinoviruses in a large proportion of samples, half of which belonged to a previously uncharacterized genetic clade. In some instances, knowledge of the detected viral and/or bacterial (co)infection could have altered clinical management
Url:
DOI: 10.1086/508551
Affiliations:
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Le document en format XML
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<front><div type="abstract">In New York State during winter 2004, there was a high incidence of influenza-like illness that tested negative both for influenza virus, by molecular methods, and for other respiratory viruses, by virus culture. Concern that a novel pathogen might be implicated led us to implement a new multiplex diagnostic tool. MassTag polymerase chain reaction resolved 26 of 79 previously negative samples, revealing the presence of rhinoviruses in a large proportion of samples, half of which belonged to a previously uncharacterized genetic clade. In some instances, knowledge of the detected viral and/or bacterial (co)infection could have altered clinical management</div>
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